Effect of Diazinon on Reversible Ki- Netic Parameters of Bovine Retinal Acetyl Cholinesterase
نویسندگان
چکیده
This current study addresses the effect of diazinon on reversible kinetic parameters such as Michaelis-Menten constant (KS) and Vmax of bovine retinal acetylcholinesterase (AChE). The Ks for the hydrolysis of acetylthiocholine iodide by AChE was increased while Vmax was decreased than the control value in the presence of the diazinon. A LineweaverBurk plot, Dixon plot and their secondary replots indicated that the nature of the inhibition was of the mixed type, i.e. a mixture of competitive and noncompetitive inhibition.
منابع مشابه
بررسی اثر حفاظتی N ـ استیل سیستئین بر سطح گلوتاتیون کبد و آنزیم استیل کولین استراز خون در موش سوری، در مسمویت حاد ناشی ازدیازینون
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